Tips for using the 4 best guns in Resident Evil 4?

Someone please give me tips on using the Chicago Typewriter, Infinite Rocket Launcher, PRL, and Handcannon please. Don't say gamefaqs, gamespot, gamespy, etc. I want tips you know work and that you have tried.

chicago typewriter - basic is like a high powered tmp,no tip in using this weapon,you just basicly spray anything that its front of you.

infinate rocket launcher - pointless having,cause you can only use it on certan areas,cause you need to be in safe range to use it.

prl - is like throwing flash bangs,and a radiation death ray to whatever is in front of it,the charged shot takes out anything in one shot,but in most casses you dont even need to use it at full power.

handcannon - a very nice magnum to have,but becomes pointless when you allready have the chicago type writer,this weapon is only at its peak when you have to play on the gamecube version of resident evil 4.

no real tips,in using any of the weapons,most of them is just point and shoot,but in the case of using the prl..its funny to blind them,then charge shot them to death,but its time consuming to wait for the charge.

Why do you need tips for how to use it?